Zekes act as the typical common enemy for survivors to fight. They ignore highly wounded survivors, seeing that they prove to be no threat to them, and that they will eventually become infected. They are extremely sensitive to sounds and will quickly rush to the area where the sound is coming from. Once alerted, they become highly aware of the presence of healthy beings and will stop at nothing to infect and/or kill them. Awaiting stimulus, they remain unaware until something alerts them to make them spring into action. In this state, the zeke are simply seen slowly walking around, lying on the ground, or just standing in place.

If left alone for some time, they go idle. They can take multiple non-headshots before falling, jump from great distances with very little harm to themselves, and climb obstacles that an ordinary human would have trouble dealing with. They appear to be completely unaware of traps set in place by humans, simply rushing to infect any healthy being in sight. In return, they have been given unnatural strength and stamina to make it easier to relentlessly chase after the living. They are perpetually aggressive and have a single goal to attack living beings. Having been infected with the zombie virus, zekes have lost all humanity. Dark veins are visible on their face, neck, and body. Their skin appears unnaturally pale and graying. A few notable examples of zekes with a noticeable appearance are construction workers who wear their high-visibility clothes and hard hats, scientists in lab coats, and soldiers in green camo uniforms. Their clothes appear disheveled, torn in a few areas, and stained in blood. As such, the undead men and women are left wearing whatever they wore at the time they were infected. Zekes are the turned human population infected with the zombie virus.

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